Dose capping enoxaparin is unjustified and denies patients with acute coronary syndromes a potentially effective treatment.
نویسندگان
چکیده
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منابع مشابه
Treatment dosing of low-molecular-weight heparins and the dose cap dilemma: considerations for patients in Canada.
BACKGROUND In Canada, there is a dose cap for weight-based treatment with low-molecular-weight (LMW) heparins. OBJECTIVE To review whether capping of LMW heparin doses is warranted for patients with obesity. METHODS English-language publications concerning the use of LMW heparin in Canada were reviewed, and the literature regarding use of these drugs at treatment doses in patients with obes...
متن کاملEnoxaparin dosing and associated risk of in-hospital bleeding and death in patients with non ST-segment elevation acute coronary syndromes.
BACKGROUND The efficacy of enoxaparin sodium in non-ST-segment elevation acute coronary syndromes is well established; however, concerns remain regarding bleeding risk. The extent to which bleeding risk is attributable to excess dosing of enoxaparin is unclear. METHODS Using data from the CRUSADE (Can Rapid Risk Stratification of Unstable Angina Patients Suppress Adverse Outcomes With Early I...
متن کاملEffects of ximelagatran, an oral direct thrombin inhibitor, r-hirudin and enoxaparin on thrombin generation and platelet activation in healthy male subjects.
OBJECTIVES The effects of ximelagatran, an oral direct thrombin inhibitor (DTI), recombinant hirudin (r-hirudin) and enoxaparin on thrombin generation and platelet activation were studied in humans. BACKGROUND Recombinant hirudin (parenteral DTI) and enoxaparin (low molecular weight heparin) have been demonstrated to be clinically effective in acute coronary syndromes. Ximelagatran is current...
متن کاملRole of low-molecular-weight heparin in the management of acute coronary syndromes.
In the past few years, several clinical trials with low-molecular-weight heparins in acute coronary syndromes without ST-segment elevation have been published. In the acute phase of treatment, enoxaparin obtained better results than unfractionated heparin, but dalteparin and nadroparin did not. Enoxaparin also obtained better results than tinzaparin. From these results, it can be assumed that t...
متن کاملبررسی تأثیر طول مدت زمان تزریق زیرجلدی انوکساپارین بر شدت درد محل تزریق بیماران سندرم حاد کرونری بستری در بخش مراقبت‌های ویژه بیمارستان افشار یزد در سال 1390
Introduction: Enoxaparin is widely used in acute coronary syndrome patients to prevent progression of coronary artery disease. Pain of injection site is the unpleasant result of subcutaneous Enoxaparin injection which causes the patient physical discomfort. One of the nurses’ tasks is applying techniques which cause the reduction of damage to the patient. This clinical trial study investigates ...
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ورودعنوان ژورنال:
- Chest
دوره 127 6 شماره
صفحات -
تاریخ انتشار 2005